Get Advances in Clinical Chemistry, Vol. 29 PDF

By Herbert E. Spiegel (ed.)

ISBN-10: 012010329X

ISBN-13: 9780120103294

The sphere of medical chemistry now encompasses features of analytical chemistry, biochemistry, scientific laboratory technology, toxicology, immunology and molecular biology. This serial offers a extra accomplished worldwide view of the present and destiny instructions of this increasing self-discipline. This quantity provides topical papers realted mostly to the kidney, melanoma and purposes of the polymerase chain response.

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Whether age-related changes occur in Cu,ZnSOD in normal rat lens is now under study in our laboratory. 3. 1. 1. Mn-SOD Protein Mn-SOD is localized in the mitochondria1 matrix and is considered to play an important role in the dismutation of 01in tissues, Due to the limited availability of human tissues, we have determined Mn-SOD levels in rat tissues. As shown in Table 2, heart, small intestine, kidney, and liver contain relatively high amounts. Interestingly, immunocytochemical distribution of Mn-SOD in rat brain hippocampus indicated that CA1 pyramidal cells were weakly stained, whereas CA3 pyramidal cells were strongly reactive, as shown in Fig.

Hutchins, G. , Weisman, H. , and Weisfeldt, M. , Reduction in experimental infarct s u e by recombinant human superoxide dismutase: Insights into the pathophysiology of reperfusion injury. Circulation 74, 1424-1433 (1986). , Purification of Cu-Zn-superoxide dismutase from human erythrocytes by immunoaffinity chromatography. J. Immunol. Methods 91, 139-143 (1986). A6. , Increase in the glucosylated form of erythrocyte Cu-Zn-superoxide dismutase in diabetes and close association of the nonenzymatic glucosylation with the enzyme activity.

Narl. Acad. Sci. 85, 73 17-732 1 (1988). Cordingley, F. , Hoftbrand, A. , Reittie, J.

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Advances in Clinical Chemistry, Vol. 29 by Herbert E. Spiegel (ed.)


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